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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 22 December 2025 Vol. No. 14 ; Issue No.714
Publications

1. Bhandari N, Devi YG, Acharya D, Bhat V, Chatterjee A, Yalshetti S, Arandkar S, Chaube BK, Shukla S (2025). MRPL47 deficiency drives mitochondrial dysfunction via ROS-p38-p21 signaling in non-small cell lung cancer.Journal of Biological Chemistry.

2. George A, Nair S, Prabhash K, Thakur S, Gera P, Singh A, Chaturvedi P, Rane S, Pradhan T, Sen S, Barkume M, Shetty D, Chaubal K, Ghosh A, Kamte S, Kode J (2026). Generation and characterization of early stage oral cancer cell line of buccal mucosa of Indian origin. Human Cell. 39: 21.

3. Joshi P, Kole L, Bavaskar M, Singh A, Shetty R, Nair S, Chaturvedi P (2025). Predictors of early versus late recurrence in post-surgical oral cancer patients. Journal of Surgical Oncology.

4. Mande R, Prasad M, Gala R, Parambil BC, Mohan R, Rane P, Chinnaswamy G (2025). Nutritional status and paediatric anthracycline early cardiotoxicity. BMJ Supportive and Palliative Care.

5. Panigrahi GC, Joshi A, Malhotra D, Gota V (2025). Mitocurcumin induces ROS-/JNK-mediated paraptosis to overcome chemoresistance in non-small cell lung cancer. Naunyn-Schmiedeberg's Archives of Pharmacology.

6. Bhat M, Narasimhan M, Shelar A, Patwardhan R, Sandur SK, Govekar R (2025). p38 MAPK-mediated suppression of Nrf2-MPC2 axis drives metabolic reprogramming which confers imatinib resistance in blast crisis phase of chronic myeloid leukemia. Experimental Cell Research.

Site of the Week

OpenNeuro is a free and open platform that shares images pertaining to MRI, MEG, EEG, iEEG, ECoG, ASL, and PET data.

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Interesting Reads

Costa LJ, Bahlis NJ, Perrot A, Nooka AK, Lu J, Pawlyn C, Mina R, Caeiro G, Kentos A, Hungria V, Reece D, Niu T, Mylin AK, Hansen CT, Teipel R, Besemer B, Dimopoulos MA, Zamagni E, Yoshihara S, Kim K, Min CK, Geerts P, Van Leeuwen-Segarceanu E, Tyczynska A, Reguera JL, Johansson M, Hansson M, Turgut M, Grey M, Sidana S, Rodriguez-Otero P, Martinez-Lopez J, Hashmi H, Carson R, Kobos R, Sun W, Lantz K, Seifert A, Briseno-Toomey D, O'Rourke L, Rubin M, Vieyra D, Kang L, Mateos MV (2025) MajesTEC-3 Trial Investigators. Teclistamab plus Daratumumab in Relapsed or Refractory Multiple Myeloma. New England Journal of Medicine.

Video of the Week
Precision Nanomedicine for Cancer: Importance of illuminating disease biology in vivo
Upcoming Events
The First Khanolkar Oration by Dr. Ajit Kumar Mohanty, Chairman, AEC & Secretary, DAE, Government of India.

January 3, 2026

At Khanolkar Auditorium, Khanolkar Shodhika, ACTREC, Kharghar, Navi Mumbai.

Workshop on Fundamentals of Cervical Cancer Screening, Colposcopy & Pre-cancer Management

January 15-16, 2026

At ACTREC, Tata Memorial Centre, Kharghar.

XXIV ANNUAL CONFERENCE Evidence Based Management of Cancers in India 2026

February 27 - March 1, 2026

At Tata Memorial Hospital, Prof. R. D. Choksi Auditorium, Parel, Mumbai.

Do You Know?

In 1998, Dennis Salmon, showed that the drug Herceptin-r improves survival of women with advanced breast cancer.

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Cancer News
C.S. Pramesh Recognized among The 100 Most Influential People in Oncology in 2025.

Oncodaily, 20/12/2025

Dr. Pramesh is internationally recognized for his commitment to reducing inequities in cancer care and improving access to high-quality treatment across diverse geographic and socioeconomic settings. He is the recipient of the Rachel Pearline Global Cancer Research Humanitarian Award...

Targeted mRNA vaccines train the immune system to destroy cancer cells.

News-Medical, 16/12/2025

The research team developed chimeric nanobodies featuring lipid tails engineered in cell factories. These nanobodies self-assemble with lipids, encapsulating mRNA to form mRNA-lipid nanoparticles with protruding nanobodies on the surface...

Restoring youth to old immune cells: mRNA therapy turns back the clock.

Nature, 17/12/2025

Compared with untreated mice, the treated mice produced more T cells and were more responsive to vaccination and to therapies that stimulate T-cell responses against cancer. Most of the effects of treatment waned once the injections stopped...

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